Arylcyclohexylamines / 3-HO-PCP

gr
Availability : IN-STOCK
Stealth-Shipping to:
DISCOUNT RATES
Price per unit
1 to 2 (gr)
USD 51.90
3 to 4 (gr)
USD 41.52
5 to 9 (gr)
USD 33.73
10 to 49 (gr)
USD 25.95
50 and + (gr)
USD 19.72

Laboratory use only.
Not for human consumption.


3-HO-PCP also known as: 3-Hydroxyphencyclidine is a dissociative of the Arylcyclohexylamine class related to Phencyclidine (PCP)

3-HO-PCP acts as a high-affinity uncompetitive antagonist of the NMDA receptor via the dizocilpine (MK-801) site (Ki = 30 nM).

It has much higher affinity than PCP for this site (Ki = 250 nM, for comparison; 8-fold difference).

The drug also has high affinity for the μ-opioid receptor (MOR) (Ki = 39–60 nM) in animal test subjects, the κ-opioid receptor (KOR) (Ki = 140 nM), and the sigma σ1 receptor (Ki = 42 nM; IC50 = 19 nM), whereas it has only low affinity for the δ-opioid receptor (Ki = 2,300 nM).

The high affinity of 3-HO-PCP for opioid receptors is unique among arylcyclohexylamines and is in contrast to PCP, which has only very low affinity for the MOR (Ki = 11,000–26,000 nM; 282- to 433-fold difference) and the other opioid receptors (Ki = 4,100 nM for the KOR and 73,000 nM for the DOR).

Although it was hypothesized that 3-HO-PCP might be a metabolite of PCP in humans, there is no evidence that this is the case.

Last stock update: December 2024 - Tags: buy online 2024, Buy 3-HO-PCP from legit research chemical vendor Lizard Labs which based in EU and sending to UK, USA, United Kingdom, Australia, New Zealand, France, Spain, Germany, United States, Sweden, Norway, Finland and all other countries in the world.
3-HO-PCP shipping proviing with undetectable parcel to ensure maximum stealthness. Order 3-HO-PCP, 3-HO-PCP with Paypal and credit card.
Lizard Labs is one of well knwon legit 3-HO-PCP vendors in research chemical market and rated 9/10 on research chemicals forums and boards.